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Basis for Gastric Cancer Diagnosis
1.Gastroscopy and biopsy
The preferred approach, enabling direct visualization and biopsy of lesions; endoscopic ultrasonography provides accurate staging.
2.CT imaging
Contrast-enhanced CT is a core staging modality, assessing depth of invasion, metastasis, and lymph node involvement.
3.Histopathological diagnosis
Biopsy pathology is the gold standard for confirmation, and immunohistochemistry can guide targeted therapy.
4.Upper gastrointestinal contrast study
Demonstrates filling defects, niche signs, and obstruction, serving as an important complement to gastroscopy.
5.Tumor marker testing
CEA and CA19-9 are used for monitoring treatment response and early warning of recurrence.
6.Staging laparoscopy
Detects occult peritoneal micrometastases and helps avoid unnecessary laparotomy.
7.PET-CT
Provides comprehensive assessment of metabolic activity and systemic metastasis and can refine staging.
8.Helicobacter pylori testing
Determines infection status; eradication therapy can reduce the risk of malignant transformation.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that early diagnosis of gastric cancer can substantially improve cure rates, whereas outcomes are limited in advanced disease. Accurate staging is the basis of individualized treatment. Experts emphasize that high-risk individuals should undergo timely gastroscopy with biopsy, and MDT-based multidisciplinary collaboration is key to optimizing diagnosis and treatment and improving prognosis.
Basis for Gastric Cancer Diagnosis
1.Gastroscopy and biopsy
The preferred approach, enabling direct visualization and biopsy of lesions; endoscopic ultrasonography provides accurate staging.
2.CT imaging
Contrast-enhanced CT is a core staging modality, assessing depth of invasion, metastasis, and lymph node involvement.
3.Histopathological diagnosis
Biopsy pathology is the gold standard for confirmation, and immunohistochemistry can guide targeted therapy.
4.Upper gastrointestinal contrast study
Demonstrates filling defects, niche signs, and obstruction, serving as an important complement to gastroscopy.
5.Tumor marker testing
CEA and CA19-9 are used for monitoring treatment response and early warning of recurrence.
6.Staging laparoscopy
Detects occult peritoneal micrometastases and helps avoid unnecessary laparotomy.
7.PET-CT
Provides comprehensive assessment of metabolic activity and systemic metastasis and can refine staging.
8.Helicobacter pylori testing
Determines infection status; eradication therapy can reduce the risk of malignant transformation.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that early diagnosis of gastric cancer can substantially improve cure rates, whereas outcomes are limited in advanced disease. Accurate staging is the basis of individualized treatment. Experts emphasize that high-risk individuals should undergo timely gastroscopy with biopsy, and MDT-based multidisciplinary collaboration is key to optimizing diagnosis and treatment and improving prognosis.