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Basis for Laryngeal Cancer Diagnosis
1.Clinical presentation assessment
Preliminary assessment is based on symptoms such as hoarseness and sore throat, together with laryngeal examination findings.
2.Video laryngoscopy
The preferred initial method. Narrow-band imaging can improve the detection rate of early lesions and guide targeted biopsy.
3.Imaging examinations
CT/MRI are used to evaluate tumor extent and depth of invasion, and PET-CT is used to screen for distant metastasis.
4.Histopathological biopsy
Tissue sampling under laryngoscopy for histopathological examination is the diagnostic gold standard.
5.Ultrasonography
Assesses cervical lymph nodes and guides needle aspiration to determine metastatic status.
6.Voice function assessment
Provides objective analysis of vocal fold function and supports voice rehabilitation planning.
7.Swallowing function assessment
Videofluoroscopic evaluation is used to assess dysphagia and prevent aspiration pneumonia.
8.HPV testing
p16/HPV-DNA testing; positivity is associated with a better prognosis and may influence treatment selection.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that early diagnosis of laryngeal cancer is pivotal. Public awareness should be improved, and accurate diagnosis should integrate laryngoscopy and imaging. Stage-adapted individualized strategies incorporating surgery and radiotherapy can substantially improve cure rates and quality of survival.
Basis for Laryngeal Cancer Diagnosis
1.Clinical presentation assessment
Preliminary assessment is based on symptoms such as hoarseness and sore throat, together with laryngeal examination findings.
2.Video laryngoscopy
The preferred initial method. Narrow-band imaging can improve the detection rate of early lesions and guide targeted biopsy.
3.Imaging examinations
CT/MRI are used to evaluate tumor extent and depth of invasion, and PET-CT is used to screen for distant metastasis.
4.Histopathological biopsy
Tissue sampling under laryngoscopy for histopathological examination is the diagnostic gold standard.
5.Ultrasonography
Assesses cervical lymph nodes and guides needle aspiration to determine metastatic status.
6.Voice function assessment
Provides objective analysis of vocal fold function and supports voice rehabilitation planning.
7.Swallowing function assessment
Videofluoroscopic evaluation is used to assess dysphagia and prevent aspiration pneumonia.
8.HPV testing
p16/HPV-DNA testing; positivity is associated with a better prognosis and may influence treatment selection.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that early diagnosis of laryngeal cancer is pivotal. Public awareness should be improved, and accurate diagnosis should integrate laryngoscopy and imaging. Stage-adapted individualized strategies incorporating surgery and radiotherapy can substantially improve cure rates and quality of survival.