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Lung Cancer Treatment Modalities
1. Surgical treatment
This includes thoracotomy, video-assisted thoracoscopic surgery (VATS), and robot-assisted surgery, and represents the main curative approach for early-stage lung cancer. Depending on tumor characteristics, lobectomy, segmentectomy, or wedge resection may be selected.
2. Kangbo Knife treatment
This is a combined cryoablation technique that destroys tumor cells through ultralow-temperature freeze–thaw cycles. It is suitable for early-stage peripheral lung cancer in patients who are unable to tolerate surgery.
3. Microwave ablation
Microwave-generated heat induces coagulative necrosis of tumor tissue. It features rapid ablation and controllable ablation zones, and is suitable for peripheral lung tumors.
4. Radiofrequency ablation
High-frequency electrical current generates heat within the tumor, resulting in thermal coagulative necrosis of cancer cells. It is a well-established minimally invasive ablation technique.
5. Iodine-125 seed implantation
Radioactive iodine-125 seeds are permanently implanted within the tumor to deliver continuous brachytherapy via sustained radiation emission, and is particularly suitable for local dose escalation.
6. Drug-eluting embolic microspheres
Using endovascular interventional techniques, drug-loaded microspheres are injected into tumor-feeding arteries to embolize vessels while locally and slowly releasing chemotherapeutic agents, enabling precision treatment.
7. This includes external beam radiotherapy and stereotactic body radiotherapy (SBRT), which can be used for curative treatment in early-stage patients or for palliative treatment in advanced disease. Precision techniques maximize sparing of normal lung tissue.
8. Chemotherapy
Platinum-based combination chemotherapy is used as neoadjuvant therapy, adjuvant therapy, treatment for advanced disease, or in combination with radiotherapy to eradicate systemic cancer cells.
9. Targeted therapy
Appropriate inhibitors are used against specific driver alterations (e.g., EGFR, ALK, ROS1), enabling precise targeting of cancer cells and significantly prolonging survival.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that treatment outcomes and prognosis are poor in advanced-stage lung cancer. The key lies in early detection and timely treatment: regular screening is recommended, and after diagnosis, an individualized plan integrating surgery, radiotherapy, systemic therapies, and minimally invasive techniques should be developed according to stage and subtype to substantially improve cure rates and patients’ quality of life.
Lung Cancer Treatment Modalities
1. Surgical treatment
This includes thoracotomy, video-assisted thoracoscopic surgery (VATS), and robot-assisted surgery, and represents the main curative approach for early-stage lung cancer. Depending on tumor characteristics, lobectomy, segmentectomy, or wedge resection may be selected.
2. Kangbo Knife treatment
This is a combined cryoablation technique that destroys tumor cells through ultralow-temperature freeze–thaw cycles. It is suitable for early-stage peripheral lung cancer in patients who are unable to tolerate surgery.
3. Microwave ablation
Microwave-generated heat induces coagulative necrosis of tumor tissue. It features rapid ablation and controllable ablation zones, and is suitable for peripheral lung tumors.
4. Radiofrequency ablation
High-frequency electrical current generates heat within the tumor, resulting in thermal coagulative necrosis of cancer cells. It is a well-established minimally invasive ablation technique.
5. Iodine-125 seed implantation
Radioactive iodine-125 seeds are permanently implanted within the tumor to deliver continuous brachytherapy via sustained radiation emission, and is particularly suitable for local dose escalation.
6. Drug-eluting embolic microspheres
Using endovascular interventional techniques, drug-loaded microspheres are injected into tumor-feeding arteries to embolize vessels while locally and slowly releasing chemotherapeutic agents, enabling precision treatment.
7. This includes external beam radiotherapy and stereotactic body radiotherapy (SBRT), which can be used for curative treatment in early-stage patients or for palliative treatment in advanced disease. Precision techniques maximize sparing of normal lung tissue.
8. Chemotherapy
Platinum-based combination chemotherapy is used as neoadjuvant therapy, adjuvant therapy, treatment for advanced disease, or in combination with radiotherapy to eradicate systemic cancer cells.
9. Targeted therapy
Appropriate inhibitors are used against specific driver alterations (e.g., EGFR, ALK, ROS1), enabling precise targeting of cancer cells and significantly prolonging survival.
Conclusion
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that treatment outcomes and prognosis are poor in advanced-stage lung cancer. The key lies in early detection and timely treatment: regular screening is recommended, and after diagnosis, an individualized plan integrating surgery, radiotherapy, systemic therapies, and minimally invasive techniques should be developed according to stage and subtype to substantially improve cure rates and patients’ quality of life.