1. New skin lesion
A newly appearing bump or spot that persists. Morphology varies by tumor subtype.
2. Noticeable change in an existing lesion
A pre-existing mole or lesion shows clear evolution in size, shape, color, or surface characteristics.
3. Ulceration and bleeding
A lesion that breaks down easily, with a raised ulcer edge; may be painless but bleeds readily and fails to heal.
4. Color variegation
Multiple colors within the same lesion (e.g., brown, black, red, white, blue), often distributed asymmetrically.
5. Itching or pain
Persistent pruritus, tenderness, or pain at the lesion site—especially when new or progressive.
6. Infiltration into surrounding tissue
The lesion becomes firm, fixed, and less mobile, suggesting deeper invasion into underlying structures.
7. Satellite lesions
Multiple small nodules developing around the primary lesion, raising concern for local spread (classically in melanoma).
8. Enlarged regional lymph nodes
Painless, firm lymph node enlargement near the drainage basin, suggesting possible metastatic involvement.
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that delayed diagnosis and treatment of skin cancer can result in significant local destruction and distant metastasis, posing a serious threat to life. Biological behavior varies across subtypes, with melanoma being the most aggressive. Improving symptom awareness, performing routine self-examinations, and obtaining prompt professional evaluation are essential to improving prognosis; any suspicious skin lesion should be assessed as early as possible.
1. New skin lesion
A newly appearing bump or spot that persists. Morphology varies by tumor subtype.
2. Noticeable change in an existing lesion
A pre-existing mole or lesion shows clear evolution in size, shape, color, or surface characteristics.
3. Ulceration and bleeding
A lesion that breaks down easily, with a raised ulcer edge; may be painless but bleeds readily and fails to heal.
4. Color variegation
Multiple colors within the same lesion (e.g., brown, black, red, white, blue), often distributed asymmetrically.
5. Itching or pain
Persistent pruritus, tenderness, or pain at the lesion site—especially when new or progressive.
6. Infiltration into surrounding tissue
The lesion becomes firm, fixed, and less mobile, suggesting deeper invasion into underlying structures.
7. Satellite lesions
Multiple small nodules developing around the primary lesion, raising concern for local spread (classically in melanoma).
8. Enlarged regional lymph nodes
Painless, firm lymph node enlargement near the drainage basin, suggesting possible metastatic involvement.
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that delayed diagnosis and treatment of skin cancer can result in significant local destruction and distant metastasis, posing a serious threat to life. Biological behavior varies across subtypes, with melanoma being the most aggressive. Improving symptom awareness, performing routine self-examinations, and obtaining prompt professional evaluation are essential to improving prognosis; any suspicious skin lesion should be assessed as early as possible.