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1. Local penile induration
An early painless indurated lesion or plaque, usually located on the glans or coronal sulcus, and easily overlooked.
2. Ulcerative or erosive lesions
A nonhealing ulcer with raised edges, an irregular base, and exudation.
3. Cauliflower-like tumor growth
An exophytic cauliflower-like mass that may necrose and bleed easily, often accompanied by foul-smelling discharge.
4. Abnormal penile discharge
Bloody or purulent malodorous discharge may accumulate, especially in patients with phimosis, making early detection more difficult.
5. Urinary obstruction symptoms
Tumor-related urethral obstruction may cause a weak urinary stream and painful urination; severe cases can lead to urinary retention.
6. Inguinal lymph node enlargement
Painless inguinal lymphadenopathy may occur initially; in later stages, nodes may become fixed or ulcerate, suggesting metastasis and poorer prognosis.
7. Penile pain or burning sensation
Persistent pain may develop in advanced disease and can radiate to the perineum, significantly affecting quality of life.
8. Systemic symptoms
In advanced stages, weight loss, fatigue, anemia, and other cachexia-related manifestations may occur due to tumor burden.
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that penile cancer is a malignant tumor that threatens men’s health. Early symptoms are often subtle, and many patients are diagnosed at intermediate or advanced stages. The disease is locally destructive and tends to spread to inguinal lymph nodes, potentially causing penile tissue loss and functional impairment. Preventive measures include good foreskin hygiene, circumcision when indicated, and HPV vaccination. Suspicious nodules or ulcers should prompt early medical evaluation, and standardized surgery with comprehensive treatment can improve treatment outcomes.
1. Local penile induration
An early painless indurated lesion or plaque, usually located on the glans or coronal sulcus, and easily overlooked.
2. Ulcerative or erosive lesions
A nonhealing ulcer with raised edges, an irregular base, and exudation.
3. Cauliflower-like tumor growth
An exophytic cauliflower-like mass that may necrose and bleed easily, often accompanied by foul-smelling discharge.
4. Abnormal penile discharge
Bloody or purulent malodorous discharge may accumulate, especially in patients with phimosis, making early detection more difficult.
5. Urinary obstruction symptoms
Tumor-related urethral obstruction may cause a weak urinary stream and painful urination; severe cases can lead to urinary retention.
6. Inguinal lymph node enlargement
Painless inguinal lymphadenopathy may occur initially; in later stages, nodes may become fixed or ulcerate, suggesting metastasis and poorer prognosis.
7. Penile pain or burning sensation
Persistent pain may develop in advanced disease and can radiate to the perineum, significantly affecting quality of life.
8. Systemic symptoms
In advanced stages, weight loss, fatigue, anemia, and other cachexia-related manifestations may occur due to tumor burden.
Jinshazhou Hospital of Guangzhou University of Chinese Medicine emphasizes that penile cancer is a malignant tumor that threatens men’s health. Early symptoms are often subtle, and many patients are diagnosed at intermediate or advanced stages. The disease is locally destructive and tends to spread to inguinal lymph nodes, potentially causing penile tissue loss and functional impairment. Preventive measures include good foreskin hygiene, circumcision when indicated, and HPV vaccination. Suspicious nodules or ulcers should prompt early medical evaluation, and standardized surgery with comprehensive treatment can improve treatment outcomes.